PEGylated sequence-controlled macromolecules using supramolecular binding to target the Taspase1/Importin α interaction
نویسندگان
چکیده
PEGylated sequence-controlled macromolecules using supramolecular binding motifs effectively disrupt Taspase1 interaction with Importin α in a concentration-dependent manner, thereby exploiting novel inhibition mechanism for this protease.
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2021
ISSN: ['1359-7345', '1364-548X']
DOI: https://doi.org/10.1039/d0cc07139k